Acne vitamin is a fat soluble vitamin, meaning it is best absorbed in the presence of some fat, commonly known as vitamin A. The main food sources of vitamin A include fish liver oil, animal liver, apricots, asparagus, beet greens, carrots, pumpkins, watermelon, cantaloupe, butternut squash, sweet potatoes, spinach, broccoli, mangoes, and green leafy vegetables. The herbs alfalfa, borage, burdock root, cayenne, and chickweed contain vitamin A.
To treat severe acne, very large doses (300,000 to 500,000 IU a day) have successfully been used by doctors. But these are very high amounts and are very toxic to the body, and should only be done when supervised by a doctor.
Because vitamin A is fat soluble, it causes the toxicity and excess amount can be stored in the body, and not excreted like water soluble vitamins. When large amounts of vitamin A are taken for extended periods of time, it can cause liver damage and nerve damage. According to experts, people can treat severe acne and avoid most of the side effects of Accutane, by taking up to 300,000 IU of non-synthetic (natural) vitamin A a day for a couple weeks and then 100,000 IU a day for a couple months. But must discontinue to use if any symptoms develop like headaches or nausea.
Precursor to vitamin A is Beta-carotene which is an antioxidant. It is the vegetable source of vitamin A and also fat soluble but nontoxic. The body converts it to vitamin A as needed. One might try supplementing with higher amounts of beta-carotene to treat acne. Beta-carotene in large amounts turns the skin an orange color, which is harmless and fades when stop taking it.